Classification Perspective
Classification Perspective
optimalClass( ..., moPropen, moMain, moCont, moClass, data, response, txName, iter = 0L, fSet = NULL, verbose = TRUE )
... |
Included to require named inputs |
moPropen |
An object of class modelObj, which defines the models and R methods to be used to obtain parameter estimates and predictions for the propensity for treatment. See ?moPropen for details. |
moMain |
An object of class modelObj, which defines the models and R methods to be used to obtain parameter estimates and predictions for for the main effects component of the outcome regression. See ?modelObj for details. NULL is an appropriate value. |
moCont |
An object of class modelObj, which defines the models and R methods to be used to obtain parameter estimates and predictions for for the contrasts component of the outcome regression. See ?modelObj for details. NULL is an appropriate value. |
moClass |
An object of class modelObj, which defines the models and R methods to be used to obtain parameter estimates and predictions for the classification. See ?modelObj for details. |
data |
A data frame of the covariates and tx histories |
response |
The response vector |
txName |
An character giving the column header of the column in data that contains the tx covariate. |
iter |
An integer See ?iter for details |
fSet |
A function or NULL. This argument allows the user to specify the subset of tx options available to a patient. See ?fSet for details of allowed structure |
verbose |
A logical If FALSE, screen prints are suppressed. |
an object of class OptimalClass
Baqun Zhang, Anastasios A. Tsiatis, Marie Davidian, Min Zhang and Eric B. Laber. "Estimating optimal tx regimes from a classification perspective." Stat 2012; 1: 103-114.
Note that this method is a single decision point, binary treatment method. For multiple decision points, can be called repeatedly.
Other single decision point methods:
earl()
,
optimalSeq()
,
owl()
,
qLearn()
,
rwl()
Other multiple decision point methods:
bowl()
,
iqLearn
,
optimalSeq()
,
qLearn()
# Load and process data set data(bmiData) # define the negative 12 month change in BMI from baseline y12 <- -100*(bmiData[,6L] - bmiData[,4L])/bmiData[,4L] # Define the propensity for treatment model and methods. moPropen <- buildModelObj(model = ~ 1, solver.method = 'glm', solver.args = list('family'='binomial'), predict.method = 'predict.glm', predict.args = list(type='response')) # classification model library(rpart) moClass <- buildModelObj(model = ~parentBMI+month4BMI+race+gender, solver.method = 'rpart', solver.args = list(method="class"), predict.args = list(type='class')) #### Second-Stage Analysis using IPW fitSS_IPW <- optimalClass(moPropen = moPropen, moClass = moClass, data = bmiData, response = y12, txName = 'A2') # outcome model moMain <- buildModelObj(model = ~parentBMI+month4BMI, solver.method = 'lm') moCont <- buildModelObj(model = ~race + parentBMI+month4BMI, solver.method = 'lm') #### Second-Stage Analysis using AIPW fitSS_AIPW <- optimalClass(moPropen = moPropen, moMain = moMain, moCont = moCont, moClass = moClass, data = bmiData, response = y12, txName = 'A2') ##Available methods # Retrieve the classification regression object classif(object = fitSS_AIPW) # Coefficients of the outcome regression objects coef(object = fitSS_AIPW) # Description of method used to obtain object DTRstep(object = fitSS_AIPW) # Estimated value of the optimal treatment regime for training set estimator(x = fitSS_AIPW) # Value object returned by outcome regression method fitObject(object = fitSS_AIPW) # Estimated optimal treatment and decision functions for training data optTx(x = fitSS_AIPW) # Estimated optimal treatment and decision functions for new data optTx(x = fitSS_AIPW, newdata = bmiData) # Value object returned by outcome regression method outcome(object = fitSS_AIPW) outcome(object = fitSS_IPW) # Plots if defined by outcome regression method dev.new() par(mfrow = c(2,4)) plot(x = fitSS_AIPW) plot(x = fitSS_AIPW, suppress = TRUE) # Retrieve the value object returned by propensity regression method propen(object = fitSS_AIPW) # Show main results of method show(object = fitSS_AIPW) # Show summary results of method summary(object = fitSS_AIPW) #### First-stage Analysis using AIPW # Define the propensity for treatment model and methods. moPropen <- buildModelObj(model = ~ 1, solver.method = 'glm', solver.args = list('family'='binomial'), predict.method = 'predict.glm', predict.args = list(type='response')) # classification model moClass <- buildModelObj(model = ~parentBMI+baselineBMI+race+gender, solver.method = 'rpart', solver.args = list(method="class"), predict.args = list(type='class')) # outcome model moMain <- buildModelObj(model = ~parentBMI+baselineBMI, solver.method = 'lm') moCont <- buildModelObj(model = ~race + parentBMI+baselineBMI, solver.method = 'lm') fitFS_AIPW <- optimalClass(moPropen = moPropen, moMain = moMain, moCont = moCont, moClass = moClass, data = bmiData, response = fitSS_AIPW, txName = 'A1') ##Available methods for fitFS_AIPW are as shown above for fitSS_AIPW
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