Compute additive log-ratio transformation
HWAlr computes the additive log-ratio transformation for
genotype counts of bi-allelic genetic markers.
HWAlr(X, zeroadj = 0.5, denominator = 2)
X |
A matrix of genotype counts (columns AA, AB and BB) |
zeroadj |
A zero adjustment parameter (0.5 by default) |
denominator |
The genotype count put in the denominator of the log-ratio (1=AA, 2=AB, 3=BB) |
A matrix or vector of log-ratio coordinates
Jan Graffelman (jan.graffelman@upc.edu)
Graffelman, J. and Egozcue, J. J. (2011) Hardy-Weinberg equilibrium: a non-parametric compositional approach. In: Vera Pawlowsky-Glahn and Antonella Buccianti (eds.) Compositional Data Analysis: Theory and Applications, John Wiley \& Sons, Ltd, pp. 207-215
X <- HWData(100,100) Y <- HWAlr(X)
Please choose more modern alternatives, such as Google Chrome or Mozilla Firefox.