Calculates incidence and bootstrap confidence intervals for immunoassay data collected with RDS
Calculates incidence and bootstrap confidence intervals for immunoassay data collected with RDS
bootstrap.incidence( rds.data, recent.variable, hiv.variable, N = NULL, weight.type = c("Gile's SS", "RDS-I", "RDS-I (DS)", "RDS-II", "Arithmetic Mean", "HCG"), mean.duration = 200, frr = 0.01, post.infection.cutoff = 730, number.of.bootstrap.samples = 1000, se.mean.duration = 0, se.frr = 0, confidence.level = 0.95, verbose = TRUE, ... )
rds.data |
an rds.data.frame |
recent.variable |
The name of the variable indicating recent infection |
hiv.variable |
The name of the variable indicating of hiv infection |
N |
Population size |
weight.type |
A string giving the type of estimator to use. The options
are |
mean.duration |
Estimated mean duration of recent infection (MDRI) (days) |
frr |
Estimated false-recent rate (FRR) |
post.infection.cutoff |
Post-infection time cut-off T, separating "true-recent" from "false-recent" results (days) |
number.of.bootstrap.samples |
The number of bootstrap samples used to construct the interval. |
se.mean.duration |
The standard error of the mean.duration estimate |
se.frr |
The standard error of the false recency estimate |
confidence.level |
The level of confidence for the interval |
verbose |
verbosity control |
... |
additional arguments to compute.weights |
The recent.variable and hiv should be the names of logical variables. Otherwise they are converted to logical using as.numeric(x) > 0.5.
This function estimates incidence using RDS sampling wieghts. Confidence intervals are constucted using HCG bootstraps. See http://www.incidence-estimation.org/ for additional information on (non-RDS) incidence estimation.
data(faux) faux$hiv <- faux$X == "blue" faux$recent <- NA faux$recent[faux$hiv] <- runif(sum(faux$hiv)) < .2 faux$recent[runif(nrow(faux)) > .5] <- NA faux$hiv[is.na(faux$recent)][c(1,6,10,21)] <- NA attr(faux,"time") <- "wave" bootstrap.incidence(faux,"recent","hiv",weight.type="RDS-II", number.of.bootstrap.samples=100)
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