Diet Restriction and Longevity
Female mice were randomly assigned to six treatment groups to investigate whether restricting dietary intake increases life expectancy. Diet treatments were:
"NP"—mice ate unlimited amount of nonpurified, standard
diet
"N/N85"—mice fed normally before and after weaning.
After weaning, ration was controlled at 85 kcal/wk
"N/R50"—normal diet before weaning and reduced calorie
diet (50 kcal/wk) after weaning
"R/R50"—reduced calorie diet of 50 kcal/wk both before
and after weaning
"N/R50 lopro"—normal diet before weaning, restricted
diet (50 kcal/wk) after weaning and dietary protein content
decreased with advancing age
"N/R40"—normal diet before weaning and reduced diet (40
Kcal/wk) after weaning.
case0501
A data frame with 349 observations on the following 2 variables.
Lifetimethe lifetime of the mice (in months)
Dietfactor variable with six levels—"NP",
"N/N85", "lopro", "N/R50", "R/R50" and
"N/R40"
Ramsey, F.L. and Schafer, D.W. (2002). The Statistical Sleuth: A Course in Methods of Data Analysis (2nd ed), Duxbury.
Weindruch, R., Walford, R.L., Fligiel, S. and Guthrie D. (1986). The Retardation of Aging in Mice by Dietary Restriction: Longevity, Cancer, Immunity and Lifetime Energy Intake, Journal of Nutrition 116(4):641–54.
str(case0501)
boxplot(Lifetime~Diet, width=c(rep(.8,6)), data=case0501,
xlab="Diet", ylab="Lifetime in months")
summary(subset(case0501, Diet=="NP", Lifetime))Please choose more modern alternatives, such as Google Chrome or Mozilla Firefox.