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gengraph

Genetic transitive graphs


Description

These functions are under development. Please email the author before using them for published work.

The function gengraph generates graphs based on genetic distances, so that pairs of entities (individuals or populations) are connected if and only if they are distant by less than a given threshold distance. Graph algorithms and classes from the igraph package are used.

gengraph is a generic function with methods for the following types of objects:
- matrix (only numeric data)
- dist
- genind objects (genetic markers, individuals)
- genpop objects (genetic markers, populations)
- DNAbin objects (DNA sequences)

Usage

gengraph(x, ...)

## S3 method for class 'matrix'
gengraph(x, cutoff=NULL, ngrp=NULL, computeAll=FALSE,
           plot=TRUE, show.graph=TRUE, col.pal=funky, truenames=TRUE,
           nbreaks=10, ...)

## S3 method for class 'dist'
gengraph(x, cutoff=NULL, ngrp=NULL, computeAll=FALSE,
           plot=TRUE, show.graph=TRUE, col.pal=funky, truenames=TRUE,
           nbreaks=10, ...)

## S3 method for class 'genind'
gengraph(x, cutoff=NULL, ngrp=NULL, computeAll=FALSE,
           plot=TRUE, show.graph=TRUE, col.pal=funky, truenames=TRUE,
           nbreaks=10, ...)

## S3 method for class 'genpop'
gengraph(x, cutoff=NULL, ngrp=NULL, computeAll=FALSE,
           plot=TRUE, show.graph=TRUE, col.pal=funky, method=1,
           truenames=TRUE, nbreaks=10, ...)

## S3 method for class 'DNAbin'
gengraph(x, cutoff=NULL, ngrp=NULL, computeAll=FALSE,
           plot=TRUE, show.graph=TRUE, col.pal=funky, truenames=TRUE,
           nbreaks=10, ...)

Arguments

x

a matrix, dist, genind, genpop, or DNAbin object. For matrix and dist, the object represents pairwise (by default, Hamming) distances between considered individuals.

cutoff

a numeric value indicating the cutoff point, i.e. the distance at which two entities are no longer connected in the garph produced by the method.

ngrp

an integer indicating the number of groups to be looked for. A message is issued if this exact number could not be found.

computeAll

a logical stating whether to investigate solutions for every (integer) cutoff point; defaults to FALSE.

plot

a logical indicating whether plots should be drawn; defaults to TRUE; this operation can take time for large, highly-connected graphs.

show.graph

a logical indicating whether the found graph should be drawn, only used in the interactive mode; this operation can take time for large, highly-connected graphs; defaults to FALSE.

col.pal

a color palette used to define group colors.

method

an integer ranging from 1 to 6 indicating the type of method to be used to derive a matrix of pairwise distances between populations; values from 1 to 5 are passed to the function dist.genpop; other values are not supported.

truenames

a logical indicating whether original labels should be used for plotting (TRUE), as opposed to indices of sequences (FALSE).

nbreaks

an integer indicating the number of breaks used by the heuristic when seeking an exact number of groups.

...

further arguments to be used by other functions; currently not used.

Value

The class gengraph is a list with the following components:

graph

a graph of class igraph.

clust

a list containing group information: $membership: an integer giving group membership; $csize: the size of each cluster; $no: the number of clusters

cutoff

the value used as a cutoff point

col

the color used to plot each group.

Author(s)

Original idea by Anne Cori and Christophe Fraser. Implementation by Thibaut Jombart t.jombart@imperial.ac.uk.

See Also

The igraph package.

Examples

if(require(ape)){
    data(woodmouse)
    g <- gengraph(woodmouse, cutoff=5)
    g
    plot(g$graph)

}

adegenet

Exploratory Analysis of Genetic and Genomic Data

v2.1.3
GPL (>= 2)
Authors
Thibaut Jombart [aut] (<https://orcid.org/0000-0003-2226-8692>), Zhian N. Kamvar [aut, cre] (<https://orcid.org/0000-0003-1458-7108>), Caitlin Collins [ctb], Roman Lustrik [ctb], Marie-Pauline Beugin [ctb], Brian J. Knaus [ctb], Peter Solymos [ctb], Vladimir Mikryukov [ctb], Klaus Schliep [ctb], Tiago Maié [ctb], Libor Morkovsky [ctb], Ismail Ahmed [ctb], Anne Cori [ctb], Federico Calboli [ctb], RJ Ewing [ctb], Frédéric Michaud [ctb], Rebecca DeCamp [ctb], Alexandre Courtiol [ctb] (<https://orcid.org/0000-0003-0637-2959>)
Initial release

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