Lymph-node-negative primary breast tumors
Tumor molecular measurements and outcome from breast cancer patients.
data(breast)
A data frame with 286 observations on the following 5 variables.
EREstrogen receptor status (factor with levels neg, pos)
ESR1Expression of the ESR1 gene (numeric)
ERBB2Expression of the ERBB2 gene (numeric)
time_survivalTime in months (numeric)
event_survivalCoded event: 0 = censored, 1 = metastasis (numeric)
ER, ESR1, and ERBB2 were measured on a tumor specimen taken at surgery (time = 0).
ESR1 and ERBB2 expression values were determined by microarray probe sets 205225_at and 216836_s_at using RMA-normalized data.
Wang Y, Klijn JG, Zhang Y, Sieuwerts AM, Look MP, Yang F, Talantov D, Timmermans M, Meijer-van Gelder ME, Yu J, Jatkoe T, Berns EM, Atkins D, Foekens JA. Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet. 2005 Feb 19-25;365(9460):671-9.
data(breast)
with(breast,
plot(ESR1, ERBB2, col = as.numeric(ER))
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