Smoking and Alzheimer's Disease
A case-control study of smoking and Alzheimer's disease.
alzheimer
A data frame with 538 observations on 3 variables.
smokinga factor with levels "None", "<10", "10-20" and
">20" (cigarettes per day).
diseasea factor with levels "Alzheimer", "Other dementias" and
"Other diagnoses".
gendera factor with levels "Female" and "Male".
Subjects with Alzheimer's disease are compared to two different control groups with respect to smoking history. The data are given in Salib and Hillier (1997, Tab. 4).
Salib, E. and Hillier, V. (1997). A case-control study of smoking and Alzheimer's disease. International Journal of Geriatric Psychiatry 12(3), 295–300. doi: 10.1002/(SICI)1099-1166(199703)12:3<295::AID-GPS476>3.0.CO;2-3
Hothorn, T., Hornik, K., van de Wiel, M. A. and Zeileis, A. (2006). A Lego system for conditional inference. The American Statistician 60(3), 257–263. doi: 10.1198/000313006X118430
## Spineplots
op <- par(no.readonly = TRUE) # save current settings
layout(matrix(1:2, ncol = 2))
spineplot(disease ~ smoking, data = alzheimer,
subset = gender == "Male", main = "Male")
spineplot(disease ~ smoking, data = alzheimer,
subset = gender == "Female", main = "Female")
par(op) # reset
## Asymptotic Cochran-Mantel-Haenszel test
cmh_test(disease ~ smoking | gender, data = alzheimer)Please choose more modern alternatives, such as Google Chrome or Mozilla Firefox.