Description

Performs the colocalisation tests described in Plagnol et al (2009) and Wallace et al (in preparation) and draws some plots.

Details

coloc.test() tests for colocalisation and returns an object of class coloc.

Author(s)

Chris Wallace <chris.wallace@cimr.cam.ac.uk>

References

Plagnol et al (2009). Statistical independence of the colocalized association signals for type 1 diabetes and RPS26 gene expression on chromosome 12q13. Biostatistics 10:327-34.

http://www.ncbi.nlm.nih.gov/pubmed/19039033

Wallace et al (2013). Statistical Testing of Shared Genetic Control for Potentially Related Traits. Genetic Epidemiology 37:802-813.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158901/

Giambartolomei et al (2014). Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics. PLOS Genet e1004383.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022491/