PREDIMED randomized trial
The PREDIMED trial (Prevención con Dieta Mediterránea) is a randomized, parallel and multicentric cohort with more than 7,000 participants who were randomly assigned to three diet groups (olive oil + mediterranean diet, nuts + mediterranean diet, and low-fat diet -control group-) and followed-up during more than 7 years.
data(predimed)
A data frame with 6324 observations on the following 15 variables:
groupa factor with levels Control MedDiet + Nuts MedDiet + VOO. Intervention group.
sexa factor with levels Male Female.Sex.
ageAge.
smokea factor with levels Never Current Former.Smoking.
bmiBody mass index.
waistWaist circumference.
wthWaist-to-height ratio.
htna factor with levels No Yes.Hypertension.
diaba factor with levels No Yes .Type-2 diabetes.
hyperchola factor with levels No Yes.Dyslipidemia.
famhista factor with levels No Yes.Family history of premature CHD.
hormoa factor with levels No Yes.Hormone-replacement therapy.
p14MeDiet Adherence score.
toeventfollow-up to main event (years).
eventa factor with levels No Yes.AMI, stroke, or CV Death.
Participants of PREDIMED study were recruited in 2003 and were revisited anually until 2010. In each visit, a large variety of different information was collected: antropometric (body mass index, age, ...), blood samples (Total cholesterol, HDL cholesterol, ...), dietary pattern consumtion using validated questionaries, treatments, etc. Also, cardiovascular events were recorded during the follow-up period. At recruitment period, each participant was assigned to each of the three diet type group. Periodically (every 6-months approximately), participants were advised to follow the diet corresponding to their group. To build this example data set approx 85% of original participants were randomly selected. For more information about this data set, see the vignette.
For more information about the study these data come from, visit http://predimed.onmedic.net/.
Estruch R, Ros E, Salas-Salvadó J, Covas MI, Corella D, Arós F, Gómez-Gracia E, Ruiz-Gutiérrez V, Fiol M, Lapetra J, Lamuela-Raventos RM, Serra-Majem L, Pintó X, Basora J, Muñoz MA, Sorlí JV, Martínez JA, Martínez-González MA; PREDIMED Study Investigators (2013). Primary prevention of cardiovascular disease with a Mediterranean diet. New England Journal of Medicine 368(14): 1279-1290.
require(compareGroups) data(predimed) summary(predimed)
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