Coxme variance function
This variance function accepts a list of matrices, which define a correlation structure for a coxme fit.
coxmeMlist(varlist, rescale = FALSE, pdcheck = TRUE, positive = TRUE)
varlist |
a list containing one or more matrix or bdsmatrix objects. |
rescale |
if TRUE, each input matrix is rescaled to have a diagonal of 1. (Kinship matrices for instance are often generated with a diagonal of .5 and would be multiplied by 2). |
pdcheck |
check each matrix to ensure that it is positive definite |
positive |
constrain coefficients to be positive. This may also be a vector of
the same length as |
If two matrices A and B were given, this fits
the variance structure
V = s1 A + s2 B,
where the variances s1 and s2 are
parameters that will be optimized by coxme,
treating A and B as fixed.
a coxme variance family object, used by coxme in the fitting process.
Terry Therneau
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