dr4pl: IC – R documentation

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IC

Obtain Inhibitory Concentrations (IC) of a dose-response curve

Description

This function obtains estimates of the IC's of a dose-response curve. Typically the IC50 parameter is of interest, but sometimes IC10 or IC90 are important aspects of a dose-response curve. By controlling the function argument, a user can obtain the IC's at various levels.

Usage

IC(object, inhib.percent)

Arguments

`object`	Object of the class 'dr4pl' for which the IC values are obtained
`inhib.percent`	Inhibited percentages at which thc IC values are obtained

Value

IC values at the inhibited percentages provided by the argument inhib.percent

Examples

data.test <- data.frame(x = c(0.0001, 0.001, 0.01, 0.1, 1),
                        y = c(10, 9, 5, 1, 0))
obj.dr4pl <- dr4pl(y ~ x,
                   data = data.test)
IC(obj.dr4pl, inhib.percent = c(10, 90))

obj.dr4pl <- dr4pl(Response ~ Dose, data = sample_data_4)  # Fit a 4PL model to data
IC(obj.dr4pl, inhib.percent = c(10, 50, 90))

dr4pl

Dose Response Data Analysis using the 4 Parameter Logistic (4pl) Model

v1.1.11

GPL (>= 2)

Authors

Justin T. Landis [aut, cre], Hyowon An [aut], Aubrey G. Bailey [aut], Dirk P. Dittmer [aut], James S. Marron [aut]

Initial release

2019-10-07

IC