Scale offsets
Ensures scale of offsets are consistent with library sizes.
## S3 method for class 'DGEList' scaleOffset(y, offset, ...) ## Default S3 method: scaleOffset(y, offset, ...)
y |
numeric vector or matrix of counts, or a |
offset |
numeric vector or matrix of offsets to be scaled. If a vector, its length must equal to the length of |
... |
other arguments that are not currently used. |
scaleOffset ensures that the scale of offsets are consistent with library sizes.
This is done by ensuring that the mean offset for each gene is the same as the mean log-library size.
The length or dimensions of offset should be consistent with the number of libraries in y.
scaleOffset.default returns a numeric vector if offset is a vector, a matrix if offset is a matrix or a CompressedMatrix object if offset is a CompressedMatrix.
scaleOffset.DGEList computes the scaled offests and store them in the offset component of the input DGEList object.
Aaron Lun, Yunshun Chen
y <- matrix(rnbinom(40,size=1,mu=100),10,4) offset <- rnorm(4) scaleOffset(y, offset)
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