Surveillance system sensitivity assuming risk-based sampling on one risk factor
Calculates risk-based surveillance system (population-level) sensitivity with a single risk factor, assuming one-stage risk-based sampling and allowing unit sensitivity to vary among risk strata.
rsu.sep.rb1rf(N, n, rr, ppr, pstar, se.u, method = "binomial")
N |
scalar or vector of the same length as that vector of |
n |
scalar or vector of the same length as that vector of |
rr |
scalar or vector of the same length as that vector of |
ppr |
scalar or vector of the same length as that vector of |
pstar |
scalar, defining the design prevalence. |
se.u |
scalar or vector of the same length as that vector of |
method |
character string indicating the method to be used. Options are |
If method = binomial
N
is ignored and values for ppr
need to be entered. Conversely, if method = hypergeometric
, ppr
is ignored and calculated from N
.
A list comprised of two elements:
se.p |
scalar, surveillance system (population-level) sensitivity estimates. |
epi |
vector, effective probability of infection estimates. |
adj.risk |
vector, adjusted relative risk estimates. |
## EXAMPLE 1: ## A cross-sectional study is to be carried out to confirm the absence of ## disease using one-stage risk based sampling. Assume a design prevalence of ## 0.10 at the cluster (herd) level and the total number of clusters in ## the population is unknown. Clusters are categorised as being either high, ## medium or low risk with the probability of disease for clusters in the ## high and medium risk area 5 and 3 times the probability of disease in the ## low risk area. The proportions of clusters in the high, medium and low risk ## area are 0.10, 0.10 and 0.80, respectively and you elect to sample five ## clusters from each of the three areas using a test with diagnostic ## sensitivity of 0.90. What is the surveillance system sensitivity? rsu.sep.rb1rf(N = NA, n = c(5,5,5), rr = c(5,3,1), ppr = c(0.10,0.10,0.80), pstar = 0.10, se.u = 0.90, method = "binomial") ## The surveillance system sensitivity is 0.94. ## EXAMPLE 2: ## Same scenario as above, but this time assume we know how many clusters are ## in the high, medium and low risk areas: 10, 10 and 80, respectively. What is ## the surveillance system sensitivity? rsu.sep.rb1rf(N = c(10,10,80), n = c(5,5,5), rr = c(5,3,1), ppr = NA, pstar = 0.10, se.u = 0.90, method = "hypergeometric") ## The surveillance system sensitivity is 0.96, almost identical to that ## calculated above where the binomial distribution was used to account for ## not knowing the size of the cluster population at risk.
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