Sample size to achieve a desired surveillance system sensitivity using pooled samples assuming representative sampling
Calculates the required sample size to achieve a desired surveilance system sensitivity assuming representative sampling, imperfect pooled test sensitivity and imperfect pooled test specificity.
rsu.sssep.rspool(k, pstar, pse, psp, se.p)
k |
scalar or vector of the same length as |
pstar |
scalar or vector of the same length as |
pse |
scalar or vector of the same length as |
psp |
scalar or vector of the same length as |
se.p |
scalar or vector (0 to 1) representing the desired surveillance system (population-level) sensitivity. |
A vector of required sample sizes.
Christensen J, Gardner I (2000). Herd-level interpretation of test results for epidemiologic studies of animal diseases. Preventive Veterinary Medicine 45: 83 - 106.
## EXAMPLE 1: ## To confirm your country's disease freedom status you intend to use a test ## applied at the herd level. The test is expensive so you decide to pool the ## samples taken from individual herds. How many pooled samples of size 5 are ## required to be 95% confident that you will have detected disease if ## 1% of herds are disease-positive? Assume a diagnostic sensitivity and ## specificity of 0.90 and 0.95 for the pooled testing regime. rsu.sssep.rspool(k = 5, pstar = 0.01, pse = 0.90, psp = 0.95, se.p = 0.95) ## A total of 32 pools (each comprised a samples from 5 herds) need to be ## tested.
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