Description

Outcomes of pregnancies exposed to coumarin derivatives. The aim is to investigate whether exposition to coumarin derivatives increases the probability of spontaneous abortions. Apart from spontaneous abortion, pregnancy may end in induced abortion or live birth, leading to a competing risks situation. Moreover, data are left-truncated as women usually enter the study several weeks after conception.

Usage

Format

A data frame with 1186 observations on the following 5 variables.

id

Identification number

entry

Entry times into the cohort

exit

Event times

group

Group. 0: control, 1: exposed to coumarin derivatives

cause

Cause of failure. 1: induced abortion, 2: life birth, 3: spontaneous abortion

Source

Meiester, R. and Schaefer, C (2008). Statistical methods for estimating the probability of spontaneous abortion in observational studies – Analyzing pregnancies exposed to coumarin derivatives. Reproductive Toxicology, 26, 31–35

Examples