Average Over Replicate Arrays
Condense a microarray data object so that technical replicate arrays are replaced with (weighted) averages.
## Default S3 method: avearrays(x, ID=colnames(x), weights=NULL) ## S3 method for class 'MAList' avearrays(x, ID=colnames(x), weights=x$weights) ## S3 method for class 'EList' avearrays(x, ID=colnames(x), weights=x$weights)
x |
a matrix-like object, usually a matrix, |
ID |
sample identifier. |
weights |
numeric matrix of non-negative weights |
A new data object is computed in which technical replicate arrays are replaced by their (weighted) averages.
For an MAList
object, the components M
and A
are both averaged in this way, as are weights
and any matrices found in object$other
.
EList
objects are similar, except that the E
component is averaged instead of M
and A
.
If x
is of mode "character"
, then the replicate values are assumed to be equal and the first is taken as the average.
A data object of the same class as x
with a column for each unique value of ID
.
Gordon Smyth
02.Classes gives an overview of data classes used in LIMMA.
x <- matrix(rnorm(8*3),8,3) colnames(x) <- c("a","a","b") avearrays(x)
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