Meta-analysis on Prevention of First Bleeding in Cirrhosis
Meta-analysis on Prevention of First Bleeding in Cirrhosis comparing beta-blocker or sclerotherapy with placebo.
A data frame with the following columns:
| id | study id |
| treat.exp | treatment in experimental group |
| logOR | log odds ratio |
| selogOR | standard error of log odds ratio |
| bleed.exp | number of bleedings in experimental group |
| n.cont | number of observations in experimental group |
| bleed.plac | number of bleedings in placebo group |
| n.plac | number of observations in placebo group |
Pagliaro L, D’Amico G et al. (1992): Prevention of first bleeding in cirrhosis. Annals in Internal Medicine, 117, 59–70
data(Pagliaro1992) sclero <- subset(Pagliaro1992, treat.exp == "Sclerotherapy") m <- metagen(logOR, selogOR, data = sclero, sm = "OR") summary(m) # Thompson & Sharp (1999), Table IV, method (2) metabias(m, method = "Egger") # Thompson & Sharp (1999), Table IV, method (3a) metabias(m, method = "Thompson") # Thompson & Sharp (1999), Table IV, method (3b) update(m, method.tau = "ML") metabias(update(m, method.tau = "ML"), method = "Thompson")
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