Amlodipine for Work Capacity
Meta-analysis on the effect of amlodipine on work capacity.
This meta-analysis is used as a data example in Hartung and Knapp (2001).
A data frame with the following columns:
| study | study label |
| n.amlo | number of observations in amlodipine group |
| mean.amlo | estimated mean in amlodipine group |
| var.amlo | variance in amlodipine group |
| n.plac | number of observations in placebo group |
| mean.plac | estimated mean in placebo group |
| var.plac | variance in placebo group |
Hartung J & Knapp G (2001): On tests of the overall treatment effect in meta-analysis with normally distributed responses. Statistics in Medicine, 20, 1771–82
data(amlodipine)
m <- metacont(n.amlo, mean.amlo, sqrt(var.amlo),
n.plac, mean.plac, sqrt(var.plac),
data = amlodipine, studlab = study)
s1 <- summary(m)
s2 <- summary(update(m, hakn = TRUE))
vars <- c("TE", "lower", "upper")
# Same results for mean difference as in Table III in Hartung and
# Knapp (2001)
#
res.md <- rbind(data.frame(s1$fixed)[vars],
data.frame(s1$random)[vars],
data.frame(s2$random)[vars])
#
res.md <- round(res.md, 5)
#
row.names(res.md) <- c("FE", "RE", "RE (HaKn)")
names(res.md) <- c("Absolute difference", "CI lower", "CI upper")
#
res.mdPlease choose more modern alternatives, such as Google Chrome or Mozilla Firefox.