Description

Enzymatic activity in the blood, for an enzyme involved in the metabolism of carcinogenic substances, among a group of 245 unrelated individuals.

Bechtel et al. (1993) identified a mixture of two skewed distributions by using maximum-likelihood estimation. Richardson and Green (1997) used a normal mixture estimated using reversible jump MCMC to estimate the distribution of the enzymatic activity.

Usage

Format

A numeric vector with observed values.

Source

http://www.stats.bris.ac.uk/~peter/mixdata

References

Bechtel, Y. C., Bonaiti-Pellie, C., Poisson, N., Magnette, J., and Bechtel, P. R.(1993). A population and family study of N-acetyltransferase using caffeine urinary metabolites. Clinical Pharmacology and Therapeutics, 54, 134–141.

Richardson, S. and Green, P. J. (1997). On Bayesian analysis of mixtures with unknown number of components (with Discussion). Journal of the Royal Statistical Society, Series B, 59, 731–792.

Examples