Network meta-analysis for chronic obstructive pulmonary disease
Network meta-analysis comparing inhaled medications in patients with chronic obstructive pulmonary disease.
A data frame with the following columns:
| id | study ID |
| treatment | treatment |
| death | mortality |
| randomized | number of individuals in treatment arm |
Dong Y-H, Lin H-H, Shau W-Y, Wu Y-C, Chang C-H, Lai M-S (2013): Comparative safety of inhaled medications in patients with chronic obstructive pulmonary disease: systematic review and mixed treatment comparison meta-analysis of randomised controlled trials. Thorax, 68, 48–56
data(Dong2013)
# Only consider first ten studies (to reduce runtime of example)
#
first10 <- subset(Dong2013, id <= 10)
# Transform data from long arm-based format to contrast-based
# format. Argument 'sm' has to be used for odds ratio as summary
# measure; by default the risk ratio is used in the metabin
# function called internally.
#
p1 <- pairwise(treatment, death, randomized, studlab = id,
data = first10, sm = "OR")
# Conduct Mantel-Haenszel network meta-analysis
#
netmetabin(p1, ref = "plac")
## Not run:
# Conduct Mantel-Haenszel network meta-analysis for the whole
# dataset
#
p2 <- pairwise(treatment, death, randomized, studlab = id,
data = Dong2013, sm = "OR")
netmetabin(p2, ref = "plac")
## End(Not run)Please choose more modern alternatives, such as Google Chrome or Mozilla Firefox.