phangorn: dist.hamming – R documentation

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dist.hamming

Pairwise Distances from Sequences

Description

dist.hamming, dist.ml and dist.logDet compute pairwise distances for an object of class phyDat. dist.ml uses DNA / AA sequences to compute distances under different substitution models.

Usage

dist.hamming(x, ratio = TRUE, exclude = "none")

dist.ml(x, model = "JC69", exclude = "none", bf = NULL, Q = NULL,
  k = 1L, shape = 1, ...)

dist.ml2(x, model = "JC69", exclude = "none", bf = NULL, Q = NULL,
  k = 1L, shape = 1, ...)

dist.logDet(x)

Arguments

`x`	An object of class `phyDat`
`ratio`	Compute uncorrected ('p') distance or character difference.
`exclude`	One of "none", "all", "pairwise" indicating whether to delete the sites with missing data (or ambiguous states). The default is handle missing data as in pml.
`model`	One of "JC69", "F81" or one of 17 amino acid models see details.
`bf`	A vector of base frequencies.
`Q`	A vector containing the lower triangular part of the rate matrix.
`k`	Number of intervals of the discrete gamma distribution.
`shape`	Shape parameter of the gamma distribution.
`...`	Further arguments passed to or from other methods.

Details

So far 17 amino acid models are supported ("WAG", "JTT", "LG", "Dayhoff", "cpREV", "mtmam", "mtArt", "MtZoa", "mtREV24", "VT","RtREV", "HIVw", "HIVb", "FLU", "Blosum62", "Dayhoff_DCMut" and "JTT_DCMut") and additional rate matrices and frequencies can be supplied.

The "F81" model uses empirical base frequencies, the "JC69" equal base frequencies. This is even the case if the data are not nucleotides.

Value

an object of class dist

Author(s)

Klaus Schliep klaus.schliep@gmail.com

References

Lockhart, P. J., Steel, M. A., Hendy, M. D. and Penny, D. (1994) Recovering evolutionary trees under a more realistic model of sequence evolution. Molecular Biology and Evolution, 11, 605–602.

Jukes TH and Cantor CR (1969). Evolution of Protein Molecules. New York: Academic Press. 21–132.

Examples

data(Laurasiatherian)
dm1 <- dist.hamming(Laurasiatherian)
tree1 <- NJ(dm1)
dm2 <- dist.logDet(Laurasiatherian)
tree2 <- NJ(dm2)
treedist(tree1,tree2)
# JC model
dm3 <- dist.ml(Laurasiatherian)
tree3 <- NJ(dm3)
treedist(tree1,tree3)
# F81 + Gamma
dm4 <- dist.ml(Laurasiatherian, model="F81", k=4, shape=.4)
tree4 <- NJ(dm4)
treedist(tree1,tree4)
treedist(tree3,tree4)

phangorn

Phylogenetic Reconstruction and Analysis

v2.7.0

GPL (>= 2)

Authors

Klaus Schliep [aut, cre] (<https://orcid.org/0000-0003-2941-0161>), Emmanuel Paradis [aut] (<https://orcid.org/0000-0003-3092-2199>), Leonardo de Oliveira Martins [aut] (<https://orcid.org/0000-0001-5247-1320>), Alastair Potts [aut], Tim W. White [aut], Cyrill Stachniss [ctb], Michelle Kendall [ctb], Keren Halabi [ctb], Richel Bilderbeek [ctb], Kristin Winchell [ctb], Liam Revell [ctb], Mike Gilchrist [ctb], Jeremy Beaulieu [ctb], Brian O'Meara [ctb], Long Qu [ctb]

Initial release