Description

Natural history of 1341 sequential patients with monoclonal gammopathy of undetermined significance (MGUS). This is a superset of the mgus data, at a later point in the accrual process

Usage

Format

A data frame with 1384 observations on the following 10 variables.

id

subject identifier

age

age at diagnosis, in years

sex

a factor with levels F M

dxyr

year of diagnosis

hgb

hemoglobin

creat

creatinine

mspike

size of the monoclonal serum splike

ptime

time until progression to a plasma cell malignancy (PCM) or last contact, in months

pstat

occurrence of PCM: 0=no, 1=yes

futime

time until death or last contact, in months

death

occurrence of death: 0=no, 1=yes

Details

This is an extension of the study found in the mgus data set, containing enrollment through 1994 and follow-up through 1999.

Source

Mayo Clinic data courtesy of Dr. Robert Kyle. All patient identifiers have been removed, age rounded to the nearest year, and follow-up times rounded to the nearest month.

References

R. Kyle, T. Therneau, V. Rajkumar, J. Offord, D. Larson, M. Plevak, and L. J. Melton III, A long-terms study of prognosis in monoclonal gammopathy of undertermined significance. New Engl J Med, 346:564-569 (2002).