Cystic Fibrosis Data
This data frame concerns families data and cystic fibrosis.
data(cfibrosis)
A data frame with 24 rows on the following 4 variables.
Over ascertained families, the kth ascertained family has s_k siblings of whom r_k are affected and a_k are ascertained.
The data set allows a classical segregation analysis
to be peformed. In particular,
to test Mendelian segregation ratios in nuclear family data.
The likelihood has similarities with seq2binomial.
The data is originally from Crow (1965) and appears as Table 2.3 of Lange (2002).
Crow, J. F. (1965) Problems of ascertainment in the analysis of family data. Epidemiology and Genetics of Chronic Disease. Public Health Service Publication 1163, Neel J. V., Shaw M. W., Schull W. J., editors, Department of Health, Education, and Welfare, Washington, DC, USA.
Lange, K. (2002) Mathematical and Statistical Methods for Genetic Analysis. Second Edition. Springer-Verlag: New York, USA.
cfibrosis summary(cfibrosis)
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