Drug-Gene Interactions
Checks for drug-gene interactions and druggable categories
drugInteractions( maf, top = 20, genes = NULL, plotType = "bar", drugs = FALSE, fontSize = 0.8 )
This function takes a list of genes and checks for known/reported drug-gene interactions or Druggable categories. All gene-drug interactions and drug claims are compiled from Drug Gene Interaction Databse. See reference for details and cite it if you use this function.
Griffith, M., Griffith, O. L., Coffman, A. C., Weible, J. V., McMichael, J. F., Spies, N. C., et. al,. 2013. DGIdb - Mining the druggable genome. Nature Methods.
laml.maf <- system.file("extdata", "tcga_laml.maf.gz", package = "maftools")
laml <- read.maf(maf = laml.maf)
drugInteractions(maf = laml)Please choose more modern alternatives, such as Google Chrome or Mozilla Firefox.