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signatureEnrichment

Performs sample stratification based on signature contribution and enrichment analysis.


Description

Performs k-means clustering to assign signature to samples and performs enrichment analysis. Note - Do not use this function. This will be removed in future updates.

Usage

signatureEnrichment(maf, sig_res, minMut = 5, useCNV = FALSE, fn = NULL)

Arguments

maf

an MAF object used for signature analysis.

sig_res

Signature results from extractSignatures

minMut

Consider only genes with minimum this number of samples mutated. Default 5.

useCNV

whether to include copy number events. Only applicable when MAF is read along with copy number data. Default TRUE if available.

fn

basename for output file. Default NULL.

Value

result list containing p-values

See Also


maftools

Summarize, Analyze and Visualize MAF Files

v2.6.05
MIT + file LICENSE
Authors
Anand Mayakonda [aut, cre] (<https://orcid.org/0000-0003-1162-687X>)
Initial release
2015-12-14

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